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GHK-Cu (Copper peptide GHK-Cu, Glycyl-L-histidyl-L-lysine:copper(II)) is a naturally occurring tripeptide-copper complex found in human plasma, saliva, and urine. Levels decline significantly with age, from ~200 ng/mL at age 20 to ~80 ng/mL by age 60. Research has investigated its effects on collagen synthesis, wound healing, skin remodeling, antioxidant enzyme expression, and anti-inflammatory activity.
These products are for laboratory research only and not intended for medical use. They must be handled by qualified professionals in controlled laboratory environments. This compound has not been evaluated by the FDA and is not approved for human or veterinary use.
These products are for laboratory research only and not intended for medical use. They must be handled by qualified professionals in controlled laboratory environments. This compound has not been evaluated by the FDA and is not approved for human or veterinary use.
Third-party tested for purity, identity, and quantity.
Lot Number
VL-1876419
Tested: Apr 5, 2026
Purity: 99.58%
GHK-Cu is typically supplied as a lyophilized (freeze-dried) powder with purity ≥98% as determined by HPLC analysis. Certificate of Analysis (CoA) documentation is available confirming identity via mass spectrometry and purity grade, appropriate for laboratory research applications.
For long-term storage, lyophilized GHK-Cu should be kept at −20°C in a desiccated, light-protected environment. Once reconstituted, working solutions should be stored at 4°C and used within a short timeframe, or aliquoted and stored at −20°C to minimize freeze-thaw degradation. These are general handling guidelines for research laboratory use.
In published in vitro research, GHK-Cu has commonly been reconstituted in sterile water or aqueous buffer systems (e.g., PBS or cell culture media) given its high water solubility. Researchers should prepare working solutions according to the specific requirements of their assay systems and confirm concentration by absorbance or other analytical methods as appropriate.
Published preclinical research has employed a range of model systems, including primary human dermal fibroblast cultures, keratinocyte cell lines, rodent wound healing models, and gene expression microarray platforms. GHK-Cu has also been investigated using bioinformatic and genomics-based approaches in silico.
No. GHK-Cu supplied by this company is strictly for in vitro and preclinical laboratory research purposes only. It is not approved for, nor intended for, human or animal therapeutic use, dietary supplementation, or any clinical application. Researchers must comply with all applicable institutional and regulatory guidelines governing research compound use.
Laboratory research has focused on GHK-Cu’s interactions with copper transport proteins, its modulation of collagen-synthesizing enzymes (including lysyl oxidase), its effects on MMP/TIMP ratios, and its influence on transcriptional programs, including those governed by NF-κB and Nrf2 pathways. These targets are studied exclusively in preclinical and in vitro research contexts.
These references are provided for research purposes only. Citations do not imply endorsement or approval of this product for any specific application.
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